EHS
OSHA / NIOSH Chemical Exposure & PPE Engine
Chemical Substitution Analysis

Trichloroethylene (TCE) vs Tetrachloroethylene (PERC)

Both chlorinated hydrocarbons are heavily targeted for regulatory prohibition by EPA TSCA and OSHA special emphasis programs.

?? Industrial Hygiene Substitution Guidance

Transition vapor degreasing systems to aqueous ultrasonics, modified alcohols, or vacuum solvent hermetic cleaning units.

Regulatory & Toxicological Matrix

Safety Parameter Trichloroethylene (TCE) Tetrachloroethylene (PERC)
CAS Number 79-01-6 127-18-4
OSHA PEL (8-Hour TWA) 100 ppm 100 ppm
NIOSH REL Lowest Feasible Concentration (Ca) Minimize workplace exposure (Ca)
ACGIH TLV (Recommended) 10 ppm (STEL 25 ppm) 25 ppm (STEL 100 ppm)
IDLH (Immediately Dangerous) Ca [1000 ppm] Ca [150 ppm]
Vapor Pressure (Volatilization) 58 mmHg (20�C) 14 mmHg (20�C)
Closed-Cup Flash Point None (Non-flammable liquid) None
Primary Health & Organ Hazards Known human carcinogen (Kidney, Liver, NHL), cardiac sensitization Probable human carcinogen, hepatotoxicity, central nervous system depression
Substitution Viability Severe Regulatory Phaseout - EPA TSCA Section 6 risk evaluation ban High Risk - Phaseout underway across dry cleaning and vapor degreasing
Full Chemical Database Profile View Trichloroethylene (TCE) Profile → View Tetrachloroethylene (PERC) Profile →
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Recommended PPE for Solvent Handling & Transfer

Whether utilizing Trichloroethylene (TCE) or Tetrachloroethylene (PERC), ensure your staff is equipped with NIOSH-certified respiratory cartridges and permeation-resistant gloves:

Planning a Chemical Substitution Pilot?

Avoid regrettable substitutions. Certified Industrial Hygienists (CIH) perform pre- and post-substitution baseline air sampling to verify that solvent alternatives truly reduce overall workforce exposure indices.